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Training periods consisted of 3 to 6 cycles. Drug teaching entailed infusion of Δ9-THC (0.one mg/kg i.v.) or rimonabant (1 mg/kg i.v.) in the very first minute of the primary of 3 cycles; sham (uninteresting force applied to the skin overlying the vascular access port) was administered in the first moment of the next cycles. Automobile teaching en

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It is concluded that EAM-2201 has the likely to result in in vivo pharmacokinetic drug interactions when co-administered with substrates of CYP2C8, CYP3A4 and UGT1A3, and is evaluated in pooled human liver microsomes. Therefore, we conclude that fitting only to strong period Homes, as is finished for most potential progress processes, normally i

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